To accelerate new drug, biologic, and medical device development and to improve efficiency of delivery of the latest breakthroughs of innovative, life-saving treatments to millions of patients, single-arm trial (SAT) applications of rare diseases or conditions supplemented by their external control arm (ECA) evidence for regulatory approvals have b

Exposure of tumor cells to ionizing radiation (IR) alters the microenvironment, Engraved Baseball particularly the fatty acid (FA) profile and activity.Moreover, abnormal FA metabolism, either catabolism or anabolism, is essential for synthesizing biological membranes and delivering molecular signals to induce ferroptotic cell death.The current rev

Premised on the notion that any educational programme for pre-service teachers pursues excellence in both academics and social justice, teacher educators must capacitate student teachers to work in areas of social justice.Pre-service teachers must subsequently be assisted to become professionally qualified teachers who are prepared to move outside

This paper addresses the relations between migrants, mobility, Queen Slat Headboard tactics, negotiation, and the contemporary definition of borders in the aftermath of 9/11.The empirical focus of this paper is how Brazilians from Alto Paranaiba journey through airports located in the Schengen area and in the British territory to London.As a main r

Abstract Esophageal adenocarcinoma (EAC) is an aggressive cancer characterized by a high risk of relapse post-surgery.Current follow-up methods (serum carcinoembryonic antigen detection and PET-CT) lack sensitivity and reliability, necessitating a novel approach.Analyzing cell-free DNA (cfDNA) from blood plasma emerges as a promising avenue.This st